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Capturing the Extracellular Matrix in 3D Color

Credit: Sarah Lipp, Purdue University, and Sarah Calve, University of Colorado, Boulder For experienced and aspiring shutterbugs alike, sometimes the best photo in the bunch turns out to be a practice...

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Biomedical Research Leads Science’s 2021 Breakthroughs

Hi everyone, I’m Larry Tabak. I’ve served as NIH’s Principal Deputy Director for over 11 years, and I will be the acting NIH director until a new permanent director is named. In my new role, my...

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How One Change to The Coronavirus Spike Influences Infectivity

Caption: Spike proteins (blue) crown SARS-CoV-2, the virus that causes COVID-19. Once the virus enters humans, the spike protein is decorated with sugars that attach to some of its amino acids,...

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NCI Support for Basic Science Paves Way for Kidney Cancer Drug Belzutifan

There’s exciting news for people with von Hippel-Lindau (VHL) disease, a rare genetic disorder that can lead to cancerous and non-cancerous tumors in multiple organs, including the brain, spinal cord,...

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Finding the ‘Tipping Point’ to Permanent Kidney Damage

Caption: Kidney organoids. Left, markers of the kidney’s filtering units called nephrons (purple, light blue, green); right, markers of the kidney’s connective tissue, or stroma (red and yellow)....

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Unraveling the Role of the Skin Microbiome in Health and Disease

Caption: Healthy human skin cells (yellow) are home to bacteria (bright pink), fungi (light blue), and other microorganisms. Credit: Alex Valm, University at Albany, NY Human skin is home to diverse...

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A Better Way to Talk About Problems with Alcohol Misuse

Credit: Shutterstock/Groupcounselingsession Did you know that language commonly used to describe alcohol misuse and alcohol use disorder (AUD) can influence treatment outcomes in people suffering from...

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Human Brain Compresses Working Memories into Low-Res ‘Summaries’

Credit: Adapted from Kwak Y., Neuron (2022) You have probably done it already a few times today. Paused to remember a password, a shopping list, a phone number, or maybe the score to last night’s...

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Tuberculosis: An Ancient Disease in Need of Modern Scientific Tools

Caption: Here I am with Paul Farmer, who was a strong voice for improving TB prevention and treatments in resource-scarce settings, when he came to NIH in 2007 to deliver my institute’s James C. Hill...

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Research to Address the Real-Life Challenges of Opioid Crisis

Caption: NIDA Director Nora Volkow (center), HEAL Initiative Director Rebecca Baker (right), and I discuss NIH’s latest efforts to combat opioid crisis. Credit: Pierce Harman for Rx Drug Abuse &...

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Testifying in the Senate for Next Year’s NIH Budget

It was an honor to testify on the President’s FY 2023 NIH budget before the U.S. Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies Committee. Also...

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Millions of Single-Cell Analyses Yield Most Comprehensive Human Cell Atlas Yet

There are 37 trillion or so cells in our bodies that work together to give us life. But it may surprise you that we still haven’t put a good number on how many distinct cell types there are within...

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Using Science To Solve Oral Health Inequities

At NIH, we have a front row seat to remarkable advances in science and technology that help Americans live longer, healthier lives. By studying the role that the mouth and saliva can play in the...

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Small Study Suggests Approved Insomnia Drug Can Aid in Opioid Recovery

Opioid use disorders (OUD) now threaten the health and lives of far too many young and adult Americans. While getting treatment is a key first step to recovery, overcoming an opioid addiction often...

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Tackling Complex Scientific Questions Requires a Team Approach

Credit: Getty Images/melitas During the COVID-19 pandemic, we have seen unprecedented, rapid scientific collaboration, as experts around the world in discrete, previously disconnected fields, have...

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Climate Change and Health Initiative to Expand Research, Build Resiliency

Credit: Athawit Ketsak/Shutterstock Climate change is a global process that affects human health in a variety of complex ways. Wildfires, heat waves, hurricanes, floods, and other climate-related...

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The Amazing Brain: Seeing Two Memories at Once

Credit: Stephanie Grella, Boston University, MA The NIH’s Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is revolutionizing our understanding of the human brain. As...

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STEM Education and Training Builds Diversity Among Next Generation of...

Credit: National Institute of General Medical Sciences, NIH Nelson Mandela said, “Education is the most powerful weapon which you can use to change the world.” At NIH’s National Institute of General...

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The Amazing Brain: Tight-Knit Connections

Credit: Sahar Ahmad, Ye Wu, and Pew-Thian Yap, The University of North Carolina, Chapel Hill You’ve likely seen pictures of a human brain showing its smooth, folded outer layer, known as the cerebral...

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Suicide Prevention Research in a Rapidly Changing World

Credit: iStock/PeopleImages As I sit down to write this blog, the COVID-19 pandemic continues to have a widespread impact, and we’re all trying to figure out our “new normal.” For some, figuring out...

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